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Single-cell RNA sequencing (scRNA-seq) is a comprehensive technical tool to analyze intracellular and intercellular inte......
AIM: To verify the hypothesis that caspase-8(Casp8), which regulates cellular apoptosis and necroptosis, is critically i......
Transcriptomic analysis reveals the regulation network of BmKrüppel homolog 1 in the oocyte developm
Krüppel homolog 1(Kr-hl),a zinc finger transcription factor,is involved in the metamorphosis and adult reproduction of ......
Chromatographic Fraction of Polygonum hydropiper Root Modulates the Expression of Transforming Growt
Objective To examine the effect of the root extract on the growth factor during early pregnancy from day 2 to day 6 of g......
The Effect of Antiseptic Cream Myogenic on Expression Levels of VEGF and bFGFmRNA in the Wounded Tis
[Objective] The mechanism of antiseptic cream myogenic was revealed from the angle of cytokines to provide theoretical b......
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Transcriptomic insights into growth promotion effect of Trichoderma afroharzianum TM2-4 microbial ag
Plant growth promoting fungi are receiving increased attention as valuable beneficial microorganisms in crop cultivation......
A major portion of the mammalian genome is transcribed to produce large numbers of noncoding RNAs(ncRNAs).During the pas......
RhoC,vascular endothelial growth factor and microvascular density in esophageal squamous cell carcin
AIM:To investigate the expression of Ras homolog(Rho)C,vascular endothelial growth factor(VEGF) and CD105 in esophageal ......
Histone ubiquitination plays a critical role in the regulation of transcription, and histone H2B monoubiquitination (H2B......
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,Transcriptome profiling reveals the association of multiple genes and pathways contributing to horm
Celery is a vital vegetable belonging to the Apiaceae family.The leaves of celery are its main edible part with high nut......
Results from a previous rice transcription mapping and the GeSTer algorithm analysis used in this in-vestigation for ric......
Isolation and Expression Patterns of Rice WRKY82 Transcription Factor Gene Responsive to Both Biotic
WRKY transcription factors are involved in the regulation of response to biotic and abiotic stresses in plants. A full-l......
High-throughput sequencing of highbush blueberry transcriptome and analysis of basic helix-loop-heli
The highbush blueberry(Vaccinium corymbosum),Duke,was used to construct a de novo transcriptome sequence library and to ......
目的 探讨Twist基因蛋白在甲状腺乳头状癌中的表达状况,寻找更特异的标记物,用于甲状腺乳头状癌(PTC)与滤泡状腺瘤(FA)和良性乳头......
目的 探讨不同神经肌肉阻滞程度对上肢前臂运动诱发电位(MEP)的影响.方法 随机选择40例自2007年1-3月期间于华山医院择期行神经外......
目的 探讨一个X-连锁迟发性脊髓骨骺发育不良(X-linked spondyloepiphyseal dysplasia tarda,SEDL)家系发病的分子机制,建立基因诊......
[目的]本文旨在阐明黄瓜植株接种促生解淀粉芽胞杆菌SQR9后其根系基因的表达谱变化特征,从植物响应微生物的角度揭示植物根际促生......
BACKGROUND Concomitant ulcerative colitis (UC) and idiopathic thrombocytopenic purpura(ITP) is a rare phenomenon. The ma......
为了揭示核桃JAZ基因家族在核桃生长发育中的作用,本研究通过构建隐马尔科夫模型与转录组数据结合的方法,在核桃全基因组数据库搜......
采用Illumina HiSeqTM2500高通量测序技术,获得泡桐维管形成层及木质部区组织转录组的109021918条clean reads(16.35 Gb)。将clean......
综述了真核生物核糖体RNA串联基因调控机制、转录预起始复合物的形成及核糖体RNA基因转录起始调控机制。......
目的应用TCD技术观察巴曲酶(DF-521)治疗频发的短暂性脑缺血发作(TIAs)与常规治疗血流动力学变化的差别.方法100例TIAs住院患者随......
以抗白粉病华东葡萄(Vitis pseudoreticulata W.T.Wang)株系白河-35-1为材料,在经葡萄白粉病病原菌(Uncinula necator(Schw.)Burr.)诱导......
目的:研究人白血病单核巨噬细胞THP-1对人胃低分化黏液腺癌MGC-803细胞NF—κB核转位的作用。方法:采用免疫荧光法检测细胞核转录因......
Transcriptomic and proteomic analysis of Locusta migratoria eggs at different embryonic stages: Comp
Temperate-zone insects typically survive winter by entering diapause. Although many aspects of insect diapause have been......
目的:探讨PPARγ是否能上调大鼠心肌细胞中miR-148b表达,以及PPARγ上调miR-148b表达是否依赖于转录水平。方法:利用吡格列酮刺激大......
目的:采集和分析上颌尖牙阻生患者牙龈组织的转录组信息,为其地域差异和病因基因理论奠定基础。方法:使用Resequencing Illumina H......
目的:比较夜磨牙患者与正常对照组经颅磁刺激(TMS)下产生的咬肌运动诱发电位(MEP)的异同。方法:纳入30名夜磨牙患者及30名健康志愿者,单脉......
采用基因枪法将耐盐的OPBP1和抗病相关的OsiWRKY转录因子共转化入水稻材料秀水11,经PCR及分子杂交分析确认目的基因已整合到水稻基......
Hepatocellular carcinoma(HCC)is one of the leading causes of death induced by cancer in the modern world and majority of......
目的利用全基因组DNA芯片技术分析牛磺酸作用下副溶血弧菌基因转录变化概况,界定受牛磺酸直接调控的基因,研究其表达调控变化规律......
为了探究Bt水稻对拟环纹豹蛛体内基因表达水平的影响,利用Illumina 2000测序平台对蜘蛛肠道进行转录组测序并分析其基因表达情况,......
目的分析不同浓度氧乐果对运动神经元agrin基因mRNA转录水平的影响。探讨有机磷中毒突触前损害的发病机制。方法体外培养大鼠脊髓......
LTR-反转录转座子是真核基因组重要的组成部分,能通过RNA中间体完成在基因组上的转座。小麦种子受低能氮离子束注入后能促进其反转......
目的:构建人乳腺癌中雌激素受体B(ERβ)3种亚型ERβ1、ERβ2和ERβ5的真核表达载体,测定不同亚型ERβ的转录活性。方法:以乳腺癌细胞MCF......
建立人多肿瘤抑制基因第二外显子cDNA的表达克隆。方法 用反转录-PCR取得MTS1第二外显cDNA,并将春直接联接入质粒pGEM-T中,构建为重组质粒pGEM-p16。结果 重组质粒......
Net是三元复合因子家族中的一员,是一种重要的转录调节因子,尤其对原癌基因c-fos的转录具有重要的调节作用,而c-fos基因与细胞的增殖......
骨桥蛋白(OPN)是一种多功能的分泌性磷酸化糖蛋白,参与机体多种生理病理学过程.多项研究表明,OPN在特定的细胞类型中的表达调控受多种因......
介绍了天然工质CO2在制冷空调领域里的应用概况,分析比较了CO2与自然工质氨、碳氢化合物作为替代工质的可行性。指出了从对环境的长......
目的对囊性胶质瘤患者Ommaya管置入手术与颅钻孔引流联合实施治疗的临床效果进行分析探究。方法将80例囊性胶质瘤患者按照数字表法......
虽然一直以来被认为是同质细胞群,不同脑区的星形胶质细胞在其生理特性方面却仍表现出差异,例如间隙连接偶联、谷氨酸摄取动力学和......
目的:探讨经颅直流电刺激(transcranial direct current stimulation,tDCS)在颅脑损伤(traumatic brain injury,TBI)导致认知功能......
固醇调节元件结合蛋白(SREBP)是重要的核转录因子之一,它能与脂质合酶基因的启动子/增强子的固醇调节元件结合,激活靶基因转录,特异性调......
为从转录组水平上分析貉免疫分子相关信息,深入了解并研究其免疫防御机制,本研究采用2代测序技术,对貉外周血单核细胞(PBMCs)进行了RNA-......
目的 探讨经颅多普勒超声(TCD)检测对脑出血患者病情程度及预后的预测价值.方法 选择首次发病且发病24 h内入院的54例脑出血患者,......
目的探究癫痫患者的dCA功能。方法研究纳入100例癫痫患者和100例年龄、性别相匹配的健康志愿者作为对照组,分别测定其dCA功能。采......
目的研究脑梗死继发癫痫的脑电图与经颅多普勒改变的相关性。方法随机选取我院2013年5月至2015年5月收治的240例脑梗死继发癫痫患......
目的探讨杂色曲霉素(ST)对机体免疫调节功能的影响。方法BALB/c小鼠随机分为正常对照组、溶剂对照组、ST3,30,300和3000μg·kg-......